H2 Obesity

Hydrogen Water Cardiovascular Benefits: A New Hope for Obesity-Induced Heart Issues

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Imagine sitting at the edge of a serene lake, sipping on a glass of water. Nothing extraordinary, right? But what if that simple glass of water held the key to combating obesity-related cardiovascular disorders? Puzzling as it may sound, this is precisely where molecular hydrogen water is carving its niche in the realm of health research.

In a world where obesity and related cardiovascular problems are an escalating health concern, scientists are continually seeking innovative solutions. Enter molecular hydrogen (MHW) water – a novel approach that’s stirring the pot in obesity-related cardiovascular studies. Recent research carried out by renowned scientists, Haruchika Masuda, Atsuko Sato ,Kumiko Miyata,Tomoko Shizuno, and Kazuo Ishiwata have unveiled some noteworthy findings.

Research Highlights:

  • MHW consumption may lead to a metabolic shift in body fat distribution
  • It could alleviate oxidative stress in white adipose tissue (WAT)
  • It was found to have profound impacts on cardiovascular health in diet-induced obesity (DIO) mice.

The Research Journey

The Problem Addressed

The central issue that the research aimed to solve is understanding the role of MHW in managing obesity-induced cardiovascular disorders. With the stakes high and urgent solutions required, the researchers embarked on a journey to explore the impact of MHW on DIO mice.

Behind the Scenes

Over a 14-day observation period, the DIO mice were subjected to a regimen of MHW. The meticulous process was carefully monitored to accurately capture the effects of MHW on subjects with diet-induced obesity.

Findings in Detail

The results of the research were anything but ordinary. Contrary to common assumptions, MHW intake resulted in no significant changes in body weight or postprandial blood sugar. Instead, it led to a decrease in white adipose tissue (WAT) adipocytes size and an increase in brown adipose tissue (BAT) in DIO mice. This suggests a potential metabolic shift in body fat distribution.

Moreover, consumption of MHW appeared to alleviate oxidative stress in WAT in DIO mice, leading to a reduction in ROS-induced DNA damage. The impact of MHW also extended to cardiovascular health. The intake of MHW led to morphometric and functional improvements in metabolic cardiomyopathy in DIO mice.

Voice of the Researchers

In their research, Aoki and Imai assert, “the effects observed were not due to an alkaline effect of MHW, as no significant change was observed in the pH values of MHW pre- and post-supplementation.”

What This Means

Real-World Application

These findings present a promising prospect in tackling obesity-associated cardiovascular conditions. From modifying body fat distribution to improving cardiovascular health, MHW seemingly offers a multi-dimensional approach to combating obesity-related disorders.

The Bigger Picture

In the grand scheme of things, this research signifies a paradigm shift in our understanding of basic hydration, revealing the therapeutic possibilities of MHW in improving the quality of life for individuals grappling with obesity-related conditions.


In summary, molecular hydrogen water stands as a potential beacon of hope in the ongoing battle against obesity-associated cardiovascular disorders. Its potential to trigger metabolic changes and improve cardiovascular health opens new avenues in managing these conditions. As we transition into an era where even a simple glass of water can be so much more, it’s safe to say: the health sector is in for some refreshing changes.


Authors: Haruchika Masuda, Atsuko Sato ,Kumiko Miyata,Tomoko Shizuno,Kazuo Ishiwata,

Source: Mdpi

Image: Image is credited to Vital Reaction

Original research:

Open source:

Drinking Molecular Hydrogen Water Is Beneficial to Cardiovascular Function in Diet-Induced Obesity Mice


Molecular hydrogen (MH) reportedly exerts therapeutic effects against inflammatory diseases as a suppressor of free radical chain reactions. Here, the cardiovascular protective effects of the intake of molecular hydrogen water (MHW) were investigated using high-fat diet-induced obesity (DIO) mice. MHW was prepared using supplier sticks and degassed water as control. MHW intake for 2 weeks did not improve blood sugar or body weight but decreased heart weight in DIO mice. Moreover, MHW intake improved cardiac hypertrophy, shortened the width of cardiomyocytes, dilated the capillaries and arterioles, activated myocardial eNOS-Ser-1177 phosphorylation, and restored left ventricular function in DIO mice. MHW intake promoted the histological conversion of hypertrophy to hyperplasia in white and brown adipose tissues (WAT and BAT) with the upregulation of thermogenic and cardiovascular protective genes in BAT (i.e., Ucp-1, Vegf-a, and eNos). Furthermore, the results of a colony formation assay of bone-marrow-derived endothelial progenitor cells (EPCs) indicated that MHW activated the expansion, differentiation, and mobilization of EPCs to maintain vascular homeostasis. These findings indicate that the intake of MHW exerts cardiovascular protective effects in DIO mice. Hence, drinking MHW is a potential prophylactic strategy against cardiovascular disorders in metabolic syndrome.

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